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Friday, June 4, 2010
Is Lasers useful for promoting hair growth?
Is Lasers useful for promoting hair growth?
Most of the time, when lasers are discussed in the context of hair, it is regarding the removal of hair. It was not until fairly recently that these devices received significant attention for their role in stimulating hair growth.
Androgenetic alopecia (AGA) affects more than 35 million men and 21 million women in the United States. Due to the relative lack of viable nonsurgical treatment options for AGA, the therapeutic focus has once again turned to lasers.
The idea of using light to stimulate hair growth was first published in the 1960s and involved mice studies (Mester E, Szende B, et al. Kiserl Orvostud. 1967;19:628-631). Despite this history, the mechanism of action of how lasers may function to prevent, stop or even promote growth in AGA is still unknown.
There is clear evidence that low-level lasers alter cell function in some manner, and low-level laser therapy (LLLT) for wound healing, pain, anti-aging and inflammation is a popular — yet relatively unproven — modality. In vitro studies with different wavelengths have shown modulation of cell activity, including increased mitochondrial activity as well as increased production of ATP.
This "stimulatory effect" of light therapy is what has driven scientists and physicians to explore low-level laser photobiomodulation for hair growth. Clinically, LLLT does seem to provide some effect, although in some treatments it is difficult to measure. When it comes to AGA, most of the focus has been on red and near-infrared light devices (600 nm to 950 nm).
Ironically, many of the reports on hair growth and lasers actually originated from laser hair removal literature. Stimulation of hair growth is an adverse event associated with hair removal with intense pulsed light (IPL), diode and alexandrite lasers. If we could predictably control this "adverse event" and elicit it in patients who actually desire more hair, a new therapeutic option could emerge.
Several authors have tried to find the common variables in those patients experiencing paradoxical hair growth during laser hair removal. The percentage of patients treated for hair removal who experience hair growth is small (less than 1 percent, from all published reports). Patients with darker skin types (IV) treated with the alexandrite laser for hair removal were more prone to hair growth than those with lighter skin types (Alajlan A, et al. J Am Acad Dermatol. 2005;53(1):85-88).
Apart from one report of several women with polycystic ovarian syndrome, there are no set risk factors for hair growth in this subset of laser hair removal patients. (Moreno-Arias G, et al. Dermatol Surg. 2002;28(11):1013-1016). In general, when treating patients for hair removal with the alexandrite, those with darker skin types will receive lower-fluence treatments to avoid dyspigmentation. It may be this relatively low-fluence therapy that, in fact, puts someone at risk for hair growth, though this has yet to be substantiated with clear data.
Hair growth studies
Laser-induced hair growth in mice has been replicated using several different devices, including a helium-neon (He-Ne) laser (Shukla S, et al. Skin Pharmacol Physiol. 2010;23(2):79-85). In this study, mice treated with the He-Ne laser had a much higher percentage of hairs in anagen phase than those not treated.
There is one published double-blind, sham device-controlled, multicentered study on hair growth (Leavitt M, et al. Clin Drug Invest. 2009;29(5):283-295). A total of 123 patients with AGA were enrolled in this well-designed, company-sponsored trial. Hair counts were completed, as were photographic assessments and patient self-assessment scores. The treatment group used a low-level laser comb (655 nm, HairMax LaserComb, Lexington International) 15 minutes a day, three days a week, for a total of 26 weeks. Hair counts at the end of six months showed a statistically significant (p<.0001) difference in hair density counts between the laser group and the sham group (+19.8 hairs/cm2 vs. -7.6 hairs/cm2 ).
There was also a statistically significant difference in the subjects' self assessments. However, blinded investigator clinical assessments did not demonstrate a statistically significant difference between the treatment and sham groups.
While LLLT with red light does stimulate terminal growth on hair count analysis, the clinical improvement is more difficult to judge. The study did not evaluate for any textural changes in hair. Textural changes may make hair appear clinically fuller, and patients may be happy with "thicker" hair that doesn't necessarily exhibit a higher hair count. It may be that longer treatment sessions or duration of the treatment is needed. It may also be more helpful clinically when used in combination with other therapies, such as hair transplant, finasteride or minoxidil.
Current devices
Currently, there are several devices available on the market that use lasers for hair growth. All utilize wavelengths of 630 nm to 670 nm and are categorized as nonsignificant risk (NSR) devices. The most popular hair-growth laser devices for home use are the Hair Max LaserComb (FDA 510(k)); the Laser Hair Brush (Sunetics); the X5 Hair Laser (Spencer Forrest); and the Aculas HB-850 (Konftec).
These devices contain different numbers and arrays of laser diodes ranging in power from 2 mW to 20 mW per diode and a total power of 20 mW to 100 mW. These units are hand-held, and the recommended treatment protocols are 10 to 15 minutes, two to three days per week. The patient must sequentially move the device during the treatment period to ensure coverage of the entire affected area.
In-office LLLT systems resemble salon dryer "hoods" and are available with higher total-dose delivery (up to 2,000 mW) than the at-home devices. One example is the Sunetics Model "G" Laser, which has an open hood composed of four panels containing a total of 107 5-mW laser diodes to treat the entire top-scalp area. These in-office treatments also come with a bigger price tag (around $3,500 to $5,000 per year for the patient).
In February, an in-office device known as the MEP-90 hair growth stimulation system (Midwest RF) received FDA 510(k) clearance for the treatment of AGA in female patients. It is currently the only device specifically studied and approved for women. At-home versions of the in-office devices are also available on the Internet, though it is difficult to ascertain the actual parameters of the device.
Recently, a home-use device with greater laser power than most in-office systems was developed under the name LaserCap (Transdermal Cap). It contains 224 5-mW laser diodes in a mesh network that covers the entire top of the scalp and fits under a hat or cap. It has a rechargeable battery so that treatment can be administered while "on the go" in a convenient, discreet fashion. The LaserCap is available to patients through physicians at a rental cost and is currently undergoing further clinical evaluation.
Optimum treatment frequency and duration have not yet been determined for hair-growth laser therapy, and it is theoretically possible that large overdoses could reverse the therapeutic effects. In other words, more power with LLLT does not necessarily translate into better results. Long-term follow-up of patients receiving LLLT for AGA is needed to determine if therapeutic benefits can be maintained with prolonged therapy.
Alopecia areata
Laser and light devices have been used in other types of hair loss, including alopecia areata (AA). Lasers for use in AA primarily function via immunomodulation, targeting the primary pathology in this condition. The eximer laser (308 nm) has shown success in several trials for this disease via the mechanism of ultraviolet immunosuppression (Al-Mutairi N. Dermatol Surg. 2007;33(12):1483-1487). While effective in AA, the eximer laser is not likely to be useful for nonimmune types of hair loss, such as AGA.
In summary, LLLT is a safe, tolerable and easy-to-use treatment option for patients with AGA. Hair counts have been shown to increase in the only double-blinded study published. Proper parameters and treatment regimens must be better elucidated in order to make this treatment more universally accepted.
At this point, LLLT (red, 630 nm to 670 nm) for AGA seems to show some effects in some patients, yet future studies are needed to optimize results by better defining treatment power, dosing and frequency. With so few reliable noninvasive therapeutic choices for AGA, laser therapy is a welcome addition.
For more links checkout
Laser Hair Removal Results at Home – Silk’n SensEpil
How to remove hair tangles
Maybe it’s just me? « Chronicles of a Selfish Mommy
Healthy Financial Habits » Blog Archive » Hair removal Washi..
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» Hair Removal with Yag Laser–Call today 716.681.2968
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FreeBlog at Sungson.com | Create an Account
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Healthinfo1.com » Blog Archive » Laser Hair Removal
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Hair Removal Questions And Answers | Hair Removal Cream For Men
Most of the time, when lasers are discussed in the context of hair, it is regarding the removal of hair. It was not until fairly recently that these devices received significant attention for their role in stimulating hair growth.
The idea of using light to stimulate hair growth was first published in the 1960s and involved mice studies (Mester E, Szende B, et al. Kiserl Orvostud. 1967;19:628-631). Despite this history, the mechanism of action of how lasers may function to prevent, stop or even promote growth in AGA is still unknown.
There is clear evidence that low-level lasers alter cell function in some manner, and low-level laser therapy (LLLT) for wound healing, pain, anti-aging and inflammation is a popular — yet relatively unproven — modality. In vitro studies with different wavelengths have shown modulation of cell activity, including increased mitochondrial activity as well as increased production of ATP.
This "stimulatory effect" of light therapy is what has driven scientists and physicians to explore low-level laser photobiomodulation for hair growth. Clinically, LLLT does seem to provide some effect, although in some treatments it is difficult to measure. When it comes to AGA, most of the focus has been on red and near-infrared light devices (600 nm to 950 nm).
Ironically, many of the reports on hair growth and lasers actually originated from laser hair removal literature. Stimulation of hair growth is an adverse event associated with hair removal with intense pulsed light (IPL), diode and alexandrite lasers. If we could predictably control this "adverse event" and elicit it in patients who actually desire more hair, a new therapeutic option could emerge.
Several authors have tried to find the common variables in those patients experiencing paradoxical hair growth during laser hair removal. The percentage of patients treated for hair removal who experience hair growth is small (less than 1 percent, from all published reports). Patients with darker skin types (IV) treated with the alexandrite laser for hair removal were more prone to hair growth than those with lighter skin types (Alajlan A, et al. J Am Acad Dermatol. 2005;53(1):85-88).
Apart from one report of several women with polycystic ovarian syndrome, there are no set risk factors for hair growth in this subset of laser hair removal patients. (Moreno-Arias G, et al. Dermatol Surg. 2002;28(11):1013-1016). In general, when treating patients for hair removal with the alexandrite, those with darker skin types will receive lower-fluence treatments to avoid dyspigmentation. It may be this relatively low-fluence therapy that, in fact, puts someone at risk for hair growth, though this has yet to be substantiated with clear data.
Hair growth studies
Laser-induced hair growth in mice has been replicated using several different devices, including a helium-neon (He-Ne) laser (Shukla S, et al. Skin Pharmacol Physiol. 2010;23(2):79-85). In this study, mice treated with the He-Ne laser had a much higher percentage of hairs in anagen phase than those not treated.
There is one published double-blind, sham device-controlled, multicentered study on hair growth (Leavitt M, et al. Clin Drug Invest. 2009;29(5):283-295). A total of 123 patients with AGA were enrolled in this well-designed, company-sponsored trial. Hair counts were completed, as were photographic assessments and patient self-assessment scores. The treatment group used a low-level laser comb (655 nm, HairMax LaserComb, Lexington International) 15 minutes a day, three days a week, for a total of 26 weeks. Hair counts at the end of six months showed a statistically significant (p<.0001) difference in hair density counts between the laser group and the sham group (+19.8 hairs/cm2 vs. -7.6 hairs/cm2 ).
There was also a statistically significant difference in the subjects' self assessments. However, blinded investigator clinical assessments did not demonstrate a statistically significant difference between the treatment and sham groups.
While LLLT with red light does stimulate terminal growth on hair count analysis, the clinical improvement is more difficult to judge. The study did not evaluate for any textural changes in hair. Textural changes may make hair appear clinically fuller, and patients may be happy with "thicker" hair that doesn't necessarily exhibit a higher hair count. It may be that longer treatment sessions or duration of the treatment is needed. It may also be more helpful clinically when used in combination with other therapies, such as hair transplant, finasteride or minoxidil.
Current devices
Currently, there are several devices available on the market that use lasers for hair growth. All utilize wavelengths of 630 nm to 670 nm and are categorized as nonsignificant risk (NSR) devices. The most popular hair-growth laser devices for home use are the Hair Max LaserComb (FDA 510(k)); the Laser Hair Brush (Sunetics); the X5 Hair Laser (Spencer Forrest); and the Aculas HB-850 (Konftec).
These devices contain different numbers and arrays of laser diodes ranging in power from 2 mW to 20 mW per diode and a total power of 20 mW to 100 mW. These units are hand-held, and the recommended treatment protocols are 10 to 15 minutes, two to three days per week. The patient must sequentially move the device during the treatment period to ensure coverage of the entire affected area.
In-office LLLT systems resemble salon dryer "hoods" and are available with higher total-dose delivery (up to 2,000 mW) than the at-home devices. One example is the Sunetics Model "G" Laser, which has an open hood composed of four panels containing a total of 107 5-mW laser diodes to treat the entire top-scalp area. These in-office treatments also come with a bigger price tag (around $3,500 to $5,000 per year for the patient).
In February, an in-office device known as the MEP-90 hair growth stimulation system (Midwest RF) received FDA 510(k) clearance for the treatment of AGA in female patients. It is currently the only device specifically studied and approved for women. At-home versions of the in-office devices are also available on the Internet, though it is difficult to ascertain the actual parameters of the device.
Recently, a home-use device with greater laser power than most in-office systems was developed under the name LaserCap (Transdermal Cap). It contains 224 5-mW laser diodes in a mesh network that covers the entire top of the scalp and fits under a hat or cap. It has a rechargeable battery so that treatment can be administered while "on the go" in a convenient, discreet fashion. The LaserCap is available to patients through physicians at a rental cost and is currently undergoing further clinical evaluation.
Optimum treatment frequency and duration have not yet been determined for hair-growth laser therapy, and it is theoretically possible that large overdoses could reverse the therapeutic effects. In other words, more power with LLLT does not necessarily translate into better results. Long-term follow-up of patients receiving LLLT for AGA is needed to determine if therapeutic benefits can be maintained with prolonged therapy.
Alopecia areata
Laser and light devices have been used in other types of hair loss, including alopecia areata (AA). Lasers for use in AA primarily function via immunomodulation, targeting the primary pathology in this condition. The eximer laser (308 nm) has shown success in several trials for this disease via the mechanism of ultraviolet immunosuppression (Al-Mutairi N. Dermatol Surg. 2007;33(12):1483-1487). While effective in AA, the eximer laser is not likely to be useful for nonimmune types of hair loss, such as AGA.
In summary, LLLT is a safe, tolerable and easy-to-use treatment option for patients with AGA. Hair counts have been shown to increase in the only double-blinded study published. Proper parameters and treatment regimens must be better elucidated in order to make this treatment more universally accepted.
At this point, LLLT (red, 630 nm to 670 nm) for AGA seems to show some effects in some patients, yet future studies are needed to optimize results by better defining treatment power, dosing and frequency. With so few reliable noninvasive therapeutic choices for AGA, laser therapy is a welcome addition.
For more links checkout
Laser Hair Removal Results at Home – Silk’n SensEpil
How to remove hair tangles
Maybe it’s just me? « Chronicles of a Selfish Mommy
Healthy Financial Habits » Blog Archive » Hair removal Washi..
Laser Hair Comb | Laser Combs
» Hair Removal with Yag Laser–Call today 716.681.2968
Hair Removal Questions And Answers | red bump on penis
what is hair Removal? Types of Hair Removal? Hair Removal Methods? Advantag..
Nothing found for Midwifery-101 3687
Laser Hair Removal Results at Home - Silk’n sensepil | Let's Gossip
Laser Hair Faq
Stop Grays with a Pill! Melt Fat with a Laser! — The Ghanaian Journa..
New Jersey Laser Hair Removal | Laser Hair Removal
How to Treat Your Skin Problems : How to Heal an Ingrown Hair
FreeBlog at Sungson.com | Create an Account
Laser Hair Faq
Silk’n SensEpil Brings Laser Hair Removal Home
Understanding the Cost of Laser Hair Removal | Post Articles Online
Laser therapy is meant for hair reduction, not removal
IPL Laser Hair Removal » Blog Archive » Laser Hair Removal F..
Permanent Makeup Eyebrow Tattoo (3deyebrow.com) Eyelash Extension (~~~~~~~~..
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DC Hair Laser Removal Washington | All About Hair
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High-Altitude Mountaineers Use All Natural Sunscreen During Himalayan Ascen..
Skin Care for Men « QV Test Drive
The Future of Hair Removal: Home Skinovations’ Silk’n SensEpil
Laser Hair Faq
Steroid injections offer ‘vision restoration’ hope for patients..
Which is the best way too get rid of unwanted facial hair in women? waxing,..
Healthinfo1.com » Blog Archive » Laser Hair Removal
Different Hair Removal Options : How to Wax Upper Lip | Hair Removal Lotion
Hair Removal Questions And Answers | Hair Removal Cream For Men
Laser Hair Removal: What are the costs, risks, side-effects and results?
Laser Hair Removal: What are the costs, risks, side-effects and results?
The cost of laser hair removal: There are several different finical facts that need to be considered when getting laser hair removal. The cost can be anywhere from $100 dollars to over a thousand. They have different prices for the different areas of your body, the physician who is going to be performing the operation, and the number of treatments you will need for a complete hair removal.
For a lot of patients three treatments will be enough for hair removal for many months, with 8-12 weeks in-between sessions. Most physicians will offer a package deal at a discount for those that need extra sessions.The side effects and risks for laser hair removal: The risks of a laser hair removal are very slim. Normal side effects rage from itching, redness, and swelling around the treatment area. Some patients have been known to have allegoric side effects from the numbing cream. A physician should be consulted if an allergic reaction presents itself after the treatment.
Results from your laser hair removal: Your upper body usually will remain hairless fro seven to eleven weeks after a full treatment (remember full treatments are normally different for every patient). Middle body treatments tend to last ten to 16 weeks, and your Leg treatment lasts 11 to 17 weeks.
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Swiss Skincare: Alchimie Forever
Swiss Skincare: Alchimie Forever
The Swiss are known for many things - their private banks, their fantastic chocolate and cheese, and their skincare products, to name a few. La Prairie, Crabtree and Evelyn, Arbonne and Swiss Perfection are just a few of the famed brands to make the jump to the United States, but we were particularly intrigued by boutique line Alchimie Forever on our recent visit to Geneva.The natural-based line offers a slew of skincare products for men and women alike based on treatments available at their flagship Forever Laser Institut, located just off the Rue du Rhone, the city's most elite shopping street.
We've been longtime fans of the brand's products - they maintain a flagship product store in Washington, DC and sell to several area spas - but were curious about the spa services. Was the Swiss experience going to be that much more phenomenal? Devoted testers we are, an appointment was made.
The spa boasts a distinctly modern vibe, with glowing lights in the spa's signature purple, blue and green colors and sleek, more than plush, chairs, in the waiting room. In keeping with the spa's medical-grade treatments, many of the pamphlets available for our perusal highlighted signature treatments involving lasers, including laser hair removal and Cryolipolysis (CoolSculpting), a new method of fat removal that literally freezes away trouble spots. Currently, Forever Laser Institut boasts the distinction of being the only Geneva spa to offer this treatment, developed by MIT and Massachusetts General Hospital.
The spa's signature treatments are mostly medical in nature, explains owner Ada Polla. The most popular bookings are for things like laser hair removal, Botox injections, and laser treatments to remove skin damage and discoloration. Of course, the spa offers wellness-oriented treatments as well, using their own signature blend of natural products that comprise the Alchimie Forever brand.
We opted for their signature facial (CHF $170), as we'd experienced the same treatment in the DC location and wanted to compare experiences. Christine, our esthetician, guided us down a low-lit hallway to a small room with music playing softly from an iPod in the corner. After leaving us to disrobe (no blankets, just a towel for our modesty), we settled in to relax. The cleansing was gentle yet thorough, and the grommage scrub left our skin feeling pleasantly refreshed, rather than abraded as in some other treatments we've experienced. Christine then applied the Kantic mask, a blueberry-based mixture said to brighten the skin, and left us to relax for about 10 minutes. The heavenly smell of blueberries helped us relax, although we would have loved mini hand, foot, or neck massage during the interlude.
When we left the spa, our skin already looked brighter, felt more hydrated, and lacked the clogged T-zone area that had built up during the previous week of travel. We'd definitely recommend a return - the service was, as can be expected in Switzerland, effective, timely, and first-rate, on par with any we'd experienced in DC. Despite being a branded spa, there was no pressure to purchase products used during the treatment, which was a welcome respite this exceptionally expensive city.
Laser Hair Removal: How Does it Work?
Laser Hair Removal: How Does it Work?
We are lucky these days to have laser hair removal for unwanted hair. In past years, people had to suffer through waxing or plucking to have hair-free skin but a laser treatment is safe, effective, and fast.
Each hair is produced by a hair root, or follicle, and some follicles produce more than one hair. The laser light is absorbed by pigment (melanin) in the hair and hair follicle, which causes the follicle to shut down. The light penetrates the skin's surface layer (the epithelium) to reach the second layer, the dermis, where there are many crucial skin structures such as sweat and oil glands, blood vessels, and a matrix of collagen and elastin which supports the skin surface to keep it smooth. Some of the skin rejuvenation procedures offered these days by cosmetic dermatologists are based on stimulating the aging skin to produce more collagen.
Hair follicles are also in the dermis. Hair grows in a cycle of three phases: a growth phase followed by an intermediate or transition phase and a shedding phase when no new hair is produced. When you have a laser hair removal procedure, the laser can only shut down the follicles that are in the growth phase.
That is the reason repeated treatments are necessary. As the follicles go in and out of their phases, each treatment can affect all those in the growth phase until you are satisfied with the degree of hair removal.
Body Areas That Can Be Treated
The hair removal laser can work on any area and most commonly works on the armpits, chin, upper lip, legs, and bikini line. In males it is also used for the chest and upper back.
Am I a Good Candidate for Laser Hair Removal?
Because laser hair removal works by the laser light being absorbed by pigment, your candidacy is determined by your hair and skin coloring and the contrast between them.
If you have black, dark brown, or dark red hair and fair skin, you would be an excellent candidate. That is because the laser light will be absorbed by the hair pigment, leaving the skin unaffected.
If you have blond, gray, light brown or light reddish hair and fair skin, you would probably not be a good candidate. Your dermatologist would decide, based on the degree of contrast between your hair and skin colors.
If you have dark skin and dark or light-colored hair, you would not be a good candidate. The laser light would be absorbed by skin pigment and would leave the hair unaffected. If your skin is darkened by a suntan, you might be a better candidate if you wait until it fades a bit.
We are lucky these days to have laser hair removal for unwanted hair. In past years, people had to suffer through waxing or plucking to have hair-free skin but a laser treatment is safe, effective, and fast.
Each hair is produced by a hair root, or follicle, and some follicles produce more than one hair. The laser light is absorbed by pigment (melanin) in the hair and hair follicle, which causes the follicle to shut down. The light penetrates the skin's surface layer (the epithelium) to reach the second layer, the dermis, where there are many crucial skin structures such as sweat and oil glands, blood vessels, and a matrix of collagen and elastin which supports the skin surface to keep it smooth. Some of the skin rejuvenation procedures offered these days by cosmetic dermatologists are based on stimulating the aging skin to produce more collagen.
Hair follicles are also in the dermis. Hair grows in a cycle of three phases: a growth phase followed by an intermediate or transition phase and a shedding phase when no new hair is produced. When you have a laser hair removal procedure, the laser can only shut down the follicles that are in the growth phase.
That is the reason repeated treatments are necessary. As the follicles go in and out of their phases, each treatment can affect all those in the growth phase until you are satisfied with the degree of hair removal.
Body Areas That Can Be Treated
The hair removal laser can work on any area and most commonly works on the armpits, chin, upper lip, legs, and bikini line. In males it is also used for the chest and upper back.
Am I a Good Candidate for Laser Hair Removal?
Because laser hair removal works by the laser light being absorbed by pigment, your candidacy is determined by your hair and skin coloring and the contrast between them.
If you have black, dark brown, or dark red hair and fair skin, you would be an excellent candidate. That is because the laser light will be absorbed by the hair pigment, leaving the skin unaffected.
If you have blond, gray, light brown or light reddish hair and fair skin, you would probably not be a good candidate. Your dermatologist would decide, based on the degree of contrast between your hair and skin colors.
If you have dark skin and dark or light-colored hair, you would not be a good candidate. The laser light would be absorbed by skin pigment and would leave the hair unaffected. If your skin is darkened by a suntan, you might be a better candidate if you wait until it fades a bit.
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